New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening
We have developed a rapid, sensitive, and inexpensive method for measuring the cellular protein content of adherent and suspension cultures in 96-well microtiter plates. The met...
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640 publications
Toward an experimental ecology of human development.
A broader approach to research in hu- j man development is proposed that focuses on the pro- gressive accommodation, throughout the life span, between the growing human organis...
Collinearity: a review of methods to deal with it and a simulation study evaluating their performance
Collinearity refers to the non independence of predictor variables, usually in a regression‐type analysis. It is a common feature of any descriptive ecological data set and can ...
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs
We have developed a new set of algorithms, collectively called “Velvet,” to manipulate de Bruijn graphs for genomic sequence assembly. A de Bruijn graph is a compact representat...
The Genotype-Tissue Expression (GTEx) project.
Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain un...
Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample
The ongoing revolution in high-throughput sequencing continues to democratize the ability of small groups of investigators to map the microbial component of the biosphere. In pa...
World Health Organization 2020 guidelines on physical activity and sedentary behaviour
Objectives To describe new WHO 2020 guidelines on physical activity and sedentary behaviour. Methods The guidelines were developed in accordance with WHO protocols. An expert Gu...
The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase
The rate of autoxidation of epinephrine and the sensitivity of this autoxidation to inhibition by superoxide dismutase were both augmented, as the pH was raised from 7.8 → 10.2....