SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Carly G.K. Ziegler , Samuel J. Allon , Sarah K. Nyquist , Carly G.K. Ziegler , Samuel J. Allon , Sarah K. Nyquist , Ian Mbano , Vincent N. Miao , Constantine N. Tzouanas , Yuming Cao , Ashraf S. Yousif , Julia Bals , Blake M. Hauser , Jared Feldman , Christoph Muus , Marc H. Wadsworth , Samuel W. Kazer , Travis K. Hughes , Benjamin A. Doran , G. James Gatter , Marko Vukovic , Faith Taliaferro , Benjamin E. Mead , Zhiru Guo , Jennifer Wang , Delphine Gras , Magali Plaisant , Meshal Ansari , Ilias Angelidis , Heiko Adler , Jennifer M. S. Sucre , Chase J. Taylor , Brian Lin , Avinash Waghray , Vanessa Mitsialis , Daniel F. Dwyer , Kathleen M. Buchheit , Joshua A. Boyce , Nora A. Barrett , Tanya M. Laidlaw , Shaina L. Carroll , Lucrezia Colonna , Victor Tkachev , Christopher W. Peterson , Alison Yu , Hengqi Zheng , Hannah P. Gideon , Caylin G. Winchell , Philana Ling Lin , Colin D. Bingle , Scott B. Snapper , Jonathan A. Kropski , Fabian J. Theis , Herbert B. Schiller , Laure‐Emmanuelle Zaragosi , Pascal Barbry , Alasdair Leslie , Hans‐Peter Kiem , JoAnne L. Flynn , Sarah M. Fortune , Bonnie Berger , Robert W. Finberg , Leslie S. Kean , Manuel Garber , Aaron G. Schmidt , Daniel Lingwood , Alex K. Shalek , José Ordovás-Montañés , Nicholas E. Banovich , Pascal Barbry , Alvis Brāzma , Tushar Desai , Thu Elizabeth Duong , Oliver Eickelberg , Christine S. Falk , Michael Farzan , Ian Glass , Muzlifah Haniffa , Péter Horváth , Deborah Hung , Naftali Kaminski , Mark A. Krasnow , Jonathan A. Kropski , Malte Kühnemund , Robert Lafyatis , Haeock Lee , Sylvie Leroy , Sten Linnarson , Joakim Lundeberg , Kerstin Meyer , Alexander Misharin , Martijn C. Nawijn , Marko Nikolić , José Ordovás-Montañés , Dana Pe’er , Joseph E. Powell , Stephen R. Quake , Jayaraj Rajagopal , Purushothama Rao Tata , Emma L. Rawlins , Aviv Regev , Paul A. Reyfman , Mauricio Rojas
2020 Cell 2,436 citations

Keywords

BiologyTMPRSS2ProteasesInterferonImmunologyFurinVirologyInterferon-stimulated geneImmune systemDiseaseInnate immune systemPathologyInfectious disease (medical specialty)Enzyme

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Year
2020
Type
article
Volume
181
Issue
5
Pages
1016-1035.e19
Citations
2436
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Carly G.K. Ziegler, Samuel J. Allon, Sarah K. Nyquist et al. (2020). SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell , 181 (5) , 1016-1035.e19. https://doi.org/10.1016/j.cell.2020.04.035

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DOI
10.1016/j.cell.2020.04.035