Stephen R. Quake

Single-molecule sequencing of an individual human genome

Microfluidics: Fluid physics at the nanoliter scale

Microfabricated integrated circuits revolutionized computation by vastly reducing the space, labor, and time required for calculations. Microfluidic systems hold similar promise...

Microfluidic Large-Scale Integration

We developed high-density microfluidic chips that contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These flu...

A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion

Producing robust and scalable fluid metering in a microfluidic device is a challenging problem. We developed a scheme for metering fluids on the picoliter scale that is scalable...

Multistep Synthesis of a Radiolabeled Imaging Probe Using Integrated Microfluidics

Microreactor technology has shown potential for optimizing synthetic efficiency, particularly in preparing sensitive compounds. We achieved the synthesis of an [ 18 F]fluoride-r...

Integrated nanoliter systems