MRC Laboratory of Molecular Biology

Sequence and organization of the human mitochondrial genome

Oxidants, oxidative stress and the biology of ageing

New tools for automated high-resolution cryo-EM structure determination in RELION-3

Here, we describe the third major release of RELION. CPU-based vector acceleration has been added in addition to GPU support, which provides flexibility in use of resources and ...

Theoretical studies of enzymic reactions: Dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme

Gctf: Real-time CTF determination and correction

Accurate estimation of the contrast transfer function (CTF) is critical for a near-atomic resolution cryo electron microscopy (cryoEM) reconstruction. Here, a GPU-accelerated co...

Artemis: sequence visualization and annotation

Abstract Summary: Artemis is a DNA sequence visualization and annotation tool that allows the results of any analysis or sets of analyses to be viewed in the context of the sequ...

Primer3Plus, an enhanced web interface to Primer3

Here we present Primer3Plus, a new web interface to the popular Primer3 primer design program as an enhanced alternative for the CGI- scripts that come with Primer3. Primer3 con...

Optimal Determination of Particle Orientation, Absolute Hand, and Contrast Loss in Single-particle Electron Cryomicroscopy

Codon—anticodon pairing: The wobble hypothesis

The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht