Publications
Explore 262 academic publications
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tu...
Structure and Function of Stream Ecosystems
General functional, interrelated components have been defined and initially dimensioned for representative stream ecosystems. Additional or alternative functional criteria are s...
An Eulerian path approach to DNA fragment assembly
For the last 20 years, fragment assembly in DNA sequencing followed the “overlap–layout–consensus” paradigm that is used in all currently available assembly tools. Although this...
The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine
The Human Gene Mutation Database (HGMD®) is a comprehensive collection of germline mutations in nuclear genes that underlie, or are associated with, human inherited disease. By ...
Predicting the clinical status of human breast cancer by using gene expression profiles
Prognostic and predictive factors are indispensable tools in the treatment of patients with neoplastic disease. For the most part, such factors rely on a few specific cell surfa...
A stagewise rejective multiple test procedure based on a modified Bonferroni test
Journal Article A stagewise rejective multiple test procedure based on a modified Bonferroni test Get access G. HOMMEL G. HOMMEL Institut für Medizinische Statistik und Dokument...
Accumulation of miR-155 and <i>BIC</i> RNA in human B cell lymphomas
We show that the microRNA miR-155 can be processed from sequences present in BIC RNA, a spliced and polyadenylated but non-protein-coding RNA that accumulates in lymphoma cells....
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
Little is known about the expression levels or function of micro-RNAs (miRNAs) in normal and neoplastic cells, although it is becoming clear that miRNAs play important roles in ...
Social networks and Internet connectivity effects
This paper explores the impact of communication media and the Internet on connectivity between people. Results from a series of social network studies of media use are used as b...
Allele-specific copy number analysis of tumors
We present an allele-specific copy number analysis of the in vivo breast cancer genome. We describe a unique bioinformatics approach, ASCAT (allele-specific copy number analysis...