Bats Are Natural Reservoirs of SARS-Like Coronaviruses
Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here w...
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1,615 publications
CRISPR–Cas12-based detection of SARS-CoV-2
An outbreak of betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 began in Wuhan, China in December 2019. COVID-19, the disease associated with SARS-CoV-2 infection,...
Early dynamics of transmission and control of COVID-19: a mathematical modelling study
An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to 95 333 confirmed cases as of March 5, 2020. Understanding the early transmission dy...
The 30 m annual land cover dataset and its dynamics in China from 1990 to 2019
Abstract. Land cover (LC) determines the energy exchange, water and carbon cycle between Earth's spheres. Accurate LC information is a fundamental parameter for the environment ...
First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial
First-line chemotherapy for advanced or metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric or gastro-oesophageal junction adenocarcinoma has a median ov...
Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
Instantaneous contact tracing New analyses indicate that severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) is more infectious and less virulent than the earlier SARS-...
Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
These remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19, as indicated by overall mortality, initi...
Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England
UK variant transmission Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the capacity to generate variants with major genomic changes. The UK variant B.1.1.7 (al...
A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes
Interleukin-1 beta (IL-1 beta)-converting enzyme cleaves the IL-1 beta precursor to mature IL-1 beta, an important mediator of inflammation. The identification of the enzyme as ...
Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020
On 5 February 2020, in Yokohama, Japan, a cruise ship hosting 3,711 people underwent a 2-week quarantine after a former passenger was found with COVID-19 post-disembarking. As a...