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Objective: To provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012.” Design: A consensus committee of 55 international expe...
Background Since at least 400 C.E., when the Mayans first used layered clays to make dyes, people have been harnessing the properties of layered materials. This gradually develo...
This is the first in a series of three articles In the past decade, qualitative methods have become more commonplace in areas such as health services research and health techn...
Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and exogenous processes, and their negative effects are neutralized by antioxidant defenses. Oxida...
Abstract Null hypothesis significance testing (NHST) is the dominant statistical approach in biology, although it has many, frequently unappreciated, problems. Most importantly,...
While most people will agree that there is much overlap between skill and luck, a full understanding of how inextricably bound the two are has yet to be attained. In principle t...
The usual general-purpose computing automaton (e.g., a Turing machine) is logically irreversible—its transition function lacks a single-valued inverse. Here it is shown that suc...
Abstract spag e d i version 1.0 is a software primarily designed to characterize the spatial genetic structure of mapped individuals or populations using genotype data of codomi...
Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design: Thirty-two intern...
[1st paragraph] At first sight, Bayesian inference with Markov Chain Monte Carlo (MCMC) appears to be straightforward. The user defines a full probability model, perhaps using o...
Interest in the role of the microbiome in human health has burgeoned over the past decade with the advent of new technologies for interrogating complex microbial communities. Th...