When Is a Trifluoromethyl Group More Lipophilic than a Methyl Group? Partition Coefficients and Selected Chemical Shifts of Aliphatic Alcohols and Trifluoroalcohols

1986 Journal of Pharmaceutical Sciences 48 citations

Keywords

TrifluoromethylPartition coefficientGroup (periodic table)ChemistryOrganic chemistryGroup contribution methodPartition (number theory)StereochemistryMedicinal chemistryMathematicsCombinatoricsPhase equilibrium

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Publication Info

Year
1986
Type
article
Volume
75
Issue
10
Pages
987-991
Citations
48
Access
Closed

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Norbert Müller (1986). When Is a Trifluoromethyl Group More Lipophilic than a Methyl Group? Partition Coefficients and Selected Chemical Shifts of Aliphatic Alcohols and Trifluoroalcohols. Journal of Pharmaceutical Sciences , 75 (10) , 987-991. https://doi.org/10.1002/jps.2600751016

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DOI
10.1002/jps.2600751016