Eliane Schweizer - Researcher Profile

Publications

2 shown

Predicting and Tuning Physicochemical Properties in Lead Optimization: Amine Basicities

Martin Morgenthaler , Eliane Schweizer , Anja Hoffmann‐Röder +11 more

Abstract This review describes simple and useful concepts for predicting and tuning the p K a values of basic amine centers, a crucial step in the optimization of physical and A...

2007 ChemMedChem 484 citations

A Fluorine Scan at the Catalytic Center of Thrombin: CF, COH, and COMe Bioisosterism and Fluorine Effects on pKa and log D Values

Manfred Kansy , François Diederich , Eliane Schweizer +7 more

Abstract A series of 16 tricyclic thrombin inhibitors was prepared by using the 1,3‐dipolar cycloaddition of azomethine ylides derived from 3‐ or 4‐hydroxyproline and 4‐bromoben...

2006 ChemMedChem 58 citations

Frequent Co-Authors

Researcher Info

h-index: 2
Publications: 2
Citations: 542
Institution: University of Vienna

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Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.