Publications
View AllGenic Intolerance to Functional Variation and the Interpretation of Personal Genomes
A central challenge in interpreting personal genomes is determining which mutations most likely influence disease. Although progress has been made in scoring the functional impa...
2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary
Symptomatic AF prior to initiation of antiarrhythmic therapy with a Class I or III antiarrhythmic medication Paroxysmal: Surgical ablation is reasonable.IIa
The Intolerance of Regulatory Sequence to Genetic Variation Predicts Gene Dosage Sensitivity
Noncoding sequence contains pathogenic mutations. Yet, compared with mutations in protein-coding sequence, pathogenic regulatory mutations are notoriously difficult to recognize...
Diabetes Prevention and Treatment Strategies
OBJECTIVE Effective interventions to prevent, delay, or remit diabetes are currently available. However, their impact on the prevalence of diabetes at the population level is un...
Affiliated Researchers
Institution Info
- Type
- healthcare
- Country
- AU
- Publications
- 10
- Citations
- 12,847
External Links
Identifiers
- ROR
- https://ror.org/005bvs909