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Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus.
Insulin-dependent diabetes mellitus (IDDM) is thought to result from the autoimmune destruction of the insulin-producing beta cells of the pancreas. Years before IDDM symptoms a...
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Recent studies have shown that insulin autoantibodies occur in patients with newly diagnosed insulin-dependent diabetes mellitus (IDDM) before exogenous insulin treatment. Our s...
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IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.
IA-2 is a 105,847 Da transmembrane protein that belongs to the protein tyrosine phosphatase family. Immunoperoxidase staining with antibody raised against IA-2 showed that this ...
Publication Info
- Year
- 1994
- Type
- article
- Volume
- 7
- Issue
- 6
- Pages
- 873-879
- Citations
- 15
- Access
- Closed
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Identifiers
- DOI
- 10.1006/jaut.1994.1071