Klotho mutant mice exhibit a set of phenotypes resembling human ageing. Although the function of Klotho remains unclear, mediation of its pleiotropic functions by putative humor...
The klotho gene encodes a novel type I membrane protein of beta-glycosidase family and is expressed principally in distal tubule cells of the kidney and choroid plexus in the br...
Homozygous klotho mutant (kl-/-) mice exhibit multiple phenotypes resembling human aging. To elucidate the molecular basis of these singular phenotypes, we focused on the mechan...
Background— Homozygous mutant mice with a defect of klotho gene expression ( kl/kl ) show multiple age-related disorders and premature death from unknown causes. Methods and Res...
h-index: Number of publications with at least h citations each.