Ronald B. DeMattos - Researcher Profile

Publications

3 shown

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

Ronald B. DeMattos , Jirong Lu , Ying Tang +10 more

Aβ Immunotherapy is a promising therapeutic approach for Alzheimer's disease. Preclinical studies demonstrate that plaque prevention is possible; however, the more relevan...

2012 Neuron 403 citations

Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease

Lawrence S. Honig , Bruno Vellas , Mark Woodward +18 more

Solanezumab at a dose of 400 mg administered every 4 weeks in patients with mild Alzheimer's disease did not significantly affect cognitive decline. (Funded by Eli Lilly; EXPEDI...

2018 New England Journal of Medicine 1012 citations

Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

Kwasi G. Mawuenyega , Carlos Cruchaga , Alison Goate +12 more

Human apoE4 increases the concentration of soluble Aβ in the brain by impairing its clearance.

2011 Science Translational Medicine 1147 citations

Frequent Co-Authors

Researcher Info

h-index: 3
Publications: 3
Citations: 2,562
Institution: Eli Lilly (Singapore)

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0009-0008-7651-1807

Impact Metrics

h-index 3

h-index: Number of publications with at least h citations each.