Publications

Fitting Linear Mixed-Effects Models Using<b>lme4</b>

Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 packa...

The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations.

In this article, we attempt to distinguish between the properties of moderator and mediator variables at a number of levels. First, we seek to make theorists and researchers awa...

Common method biases in behavioral research: A critical review of the literature and recommended remedies.

Interest in the problem of method biases has a long history in the behavioral sciences. Despite this, a comprehensive summary of the potential sources of method biases and how t...

Gradient-based learning applied to document recognition

Multilayer neural networks trained with the back-propagation algorithm constitute the best example of a successful gradient based learning technique. Given an appropriate networ...

Designing complex, dynamic yet multi-functional materials and devices is challenging because the design spaces for these materials have numerous interdependent and often conflic...

UCSF Chimera—A visualization system for exploratory research and analysis

Abstract The design, implementation, and capabilities of an extensible visualization system, UCSF Chimera, are discussed. Chimera is segmented into a core that provides basic se...

The Hospital Anxiety and Depression Scale

ABSTRACT– A self‐assessment scale has been developed and found to be a reliable instrument for detecting states of depression and anxiety in the setting of an hospital medical o...

XGBoost

Tree boosting is a highly effective and widely used machine learning method.\nIn this paper, we describe a scalable end-to-end tree boosting system called\nXGBoost, which is use...

Highly accurate protein structure prediction with AlphaFold

Abstract Proteins are essential to life, and understanding their structure can facilitate a mechanistic understanding of their function. Through an enormous experimental effort ...

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

CLUSTAL X is a new windows interface for the widely-used progressive multiple sequence alignment program CLUSTAL W. The new system is easy to use, providing an integrated system...

Structural equation modeling in practice: A review and recommended two-step approach.

In this article, we provide guidance for substantive researchers on the use of structural equation modeling in practice for theory testing and development. We present a comprehe...

Applied logistic regression

From the reviews of the First Edition. An interesting, useful, and well-written book on logistic regression models... Hosmer and Lemeshow have used very little mathematics, have...