The Sequence of the Human Genome
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp ...
Publications
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2,564 publications
Modernity and Self-Identity: Self and Society in the Late Modern Age
The reflexivity of modernity extends into core of the self. Put in another way, in the context of a post-traditional order, the self becomes a reflexive project. One concerns th...
A Global Geometric Framework for Nonlinear Dimensionality Reduction
Scientists working with large volumes of high-dimensional data, such as global climate patterns, stellar spectra, or human gene distributions, regularly confront the problem of ...
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
The CONSORT statement is used worldwide to improve the reporting of randomised controlled trials. Kenneth Schulz and colleagues describe the latest version, CONSORT 2010, which ...
APACHE II
This paper presents the form and validation results of APACHE II, a severity of disease classification system. APACHE II uses a point score based upon initial values of 12 routi...
Scoping studies: advancing the methodology
Specific recommendations to clarify and enhance this methodology are outlined for each stage of the Arksey and O'Malley framework. Continued debate and development about scoping...
A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules
Abstract: We present the derivation of a new molecular mechanical force field for simulating the structures, conformational energies, and interaction energies of proteins, nucle...