Publications

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

Velvet: Algorithms for de novo short read assembly using de Bruijn graphs

We have developed a new set of algorithms, collectively called “Velvet,” to manipulate de Bruijn graphs for genomic sequence assembly. A de Bruijn graph is a compact representat...

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

A high-capacity system was developed to monitor the expression of many genes in parallel. Microarrays prepared by high-speed robotic printing of complementary DNAs on glass were...

In vitro selection of RNA molecules that bind specific ligands

Sequence and organization of the human mitochondrial genome

Gene expression profiling predicts clinical outcome of breast cancer

MicroRNA expression profiles classify human cancers

The Genotype-Tissue Expression (GTEx) project.

Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain un...

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

The ongoing revolution in high-throughput sequencing continues to democratize the ability of small groups of investigators to map the microbial component of the biosphere. In pa...

The mutational constraint spectrum quantified from variation in 141,456 humans

The biology <b>,</b> function <b>,</b> and biomedical applications of exosomes

Clinical uses of cellular communication Exosomes are a type of extracellular vesicle that contain constituents (protein, DNA, and RNA) of the cells that secrete them. They are t...

Focal Loss for Dense Object Detection

The highest accuracy object detectors to date are based on a two-stage approach popularized by R-CNN, where a classifier is applied to a sparse set of candidate object locations...