Fragment assembly with short reads
Abstract Motivation: Current DNA sequencing technology produces reads of about 500–750 bp, with typical coverage under 10×. New sequencing technologies are emerging that produce...
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152 publications
Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment.
A novel cDNA, IA-2beta, was isolated from a mouse neonatal brain library. The predicted protein sequence revealed an extracellular domain, a transmembrane region, and an intrace...
Deformable Part Descriptors for Fine-Grained Recognition and Attribute Prediction
Recognizing objects in fine-grained domains can be extremely challenging due to the subtle differences between subcategories. Discriminative markings are often highly localized,...
Insulin Sensitivity and Insulin Binding to Monocytes in Maturity-Onset Diabetes
Tissue sensitive to insulin and insulin binding to monocytes were evaluated in 15 nonobese maturity-onset diabetics and in 16 healthy controls. Insulin sensitivity was determine...
On the Smoothing of Probability Density Functions
Summary We consider the estimation of a probability density function by linear smoothing of the observed density. A basis for estimation is obtained by assuming that the ordinat...
Effect of Drake and Panamanian Gateways on the circulation of an ocean model
Geologic studies indicate that prior to ∼40 Ma the Drake Passage was closed and the Central American Isthmus was open. The effect of these changes has been examined in an ocean ...
Beta Process Joint Dictionary Learning for Coupled Feature Spaces with Application to Single Image Super-Resolution
This paper addresses the problem of learning over-complete dictionaries for the coupled feature spaces, where the learned dictionaries also reflect the relationship between the ...
Goodness-of-Fit Testing for Latent Class Models
Latent class models with sparse contingency tables can present problems for model comparison and selection, because under these conditions the distributions of goodness-of-fit i...
Radiocarbon calibration beyond 20,000 <sup>14</sup>C yr B.P. by means of planktonic foraminifera of the Iberian Margin
We present a new set of 14 C ages obtained by accelerator mass spectrometry (AMS) on planktonic foraminifera from a deep-sea core collected off the Iberian Margin (MD952042). Th...
Liquidity and the 1987 stock market crash
T he Crash of October 1987 was a puzzling event puzzling not only for what happened on October 19, but also for what subsequently did not happen. In spite of the magnitude and m...
EFFECTS OF INSTRUCTIONS AND REINFORCEMENT‐FEEDBACK ON HUMAN OPERANT BEHAVIOR MAINTAINED BY FIXED‐INTERVAL REINFORCEMENT<sup>1</sup>
In three experiments, human subjects were trained on a five‐component multiple schedule with different fixed intervals of monetary reinforcement scheduled in the different compo...
Hierarchical Phylogenetic Models for Analyzing Multipartite Sequence Data
Debate exists over how to incorporate information from multipartite sequence data in phylogenetic analyses. Strict combined-data approaches argue for concatenation of all partit...