Calculating statistical power in Mendelian randomization studies
In Mendelian randomization (MR) studies, where genetic variants are used as proxy measures for an exposure trait of interest, obtaining adequate statistical power is frequently ...
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178 publications
AWTY (are we there yet?): a system for graphical exploration of MCMC convergence in Bayesian phylogenetics
Abstract Summary: A key element to a successful Markov chain Monte Carlo (MCMC) inference is the programming and run performance of the Markov chain. However, the explicit use o...
Is Social Capital Declining in the United States? A Multiple Indicator Assessment
Despite a great deal of interest in a possible decline of social capital in the United States, scholars have not reached a consensus on the trend. This article improves upon pre...
Dynamic disorder in methylammoniumtrihalogenoplumbates (II) observed by millimeter-wave spectroscopy
The temperature-dependent structure of crystalline methylammoniumtrihalogenoplumbates (II)—CH3NH+3PbX−3 (X=Cl, Br, I)—as determined by x-ray diffraction, is compared with measur...
Computer Simulation of Molecular Dynamics: Methodology, Applications, and Perspectives in Chemistry
Abstract During recent decades it has become feasible to simulate the dynamics of molecular systems on a computer. The method of molecular dynamics (MD) solves Newton's equation...
The National Lung Screening Trial: Overview and Study Design
The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older c...
Markov Chains
Markov chains are central to the understanding of random processes. This is not only because they pervade the applications of random processes, but also because one can calculat...
Two‐Dimensional Dielectric Nanosheets: Novel Nanoelectronics From Nanocrystal Building Blocks
Abstract Two‐dimensional (2D) nanosheets, which possess atomic or molecular thickness and infinite planar lengths, are regarded as the thinnest functional nanomaterials. The rec...
The future of optimism.
Recent theoretical discussions of optimism as an inherent aspect of human nature converge with empirical investigations of optimism as an individual difference to show that opti...
Stalking the perfect measure of implicit self-esteem: The blind men and the elephant revisited?
Recent interest in the implicit self-esteem construct has led to the creation and use of several new assessment tools whose psychometric properties have not been fully explored....
A Redetermination of the Relative Abundances of the Isotopes of Carbon, Nitrogen, Oxygen, Argon, and Potassium
Essentially pure samples of ${\mathrm{A}}^{36}$ and ${\mathrm{A}}^{40}$ have been produced by thermal diffusion and used for the preparation of synthetic argon isotope mixtures ...
Mendelian randomization as an instrumental variable approach to causal inference
In epidemiological research, the causal effect of a modifiable phenotype or exposure on a disease is often of public health interest. Randomized controlled trials to investigate...