Two-, six-, and 12-minute walking tests in respiratory disease.
Over the ensuing seven months she had three more clinical relapses, each accompanied by reappearance in the stools of either the organism or its cytotoxin, or both.Each improvem...
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150 publications
Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates
Vaccination of nonhuman primates with mRNA-1273 induced robust SARS-CoV-2 neutralizing activity, rapid protection in the upper and lower airways, and no pathologic changes in th...
Establishing rigour in qualitative research: the decision trail
The aim of this paper is to show the way in which the decision trail of a qualitative research process can be maintained. It is argued that the trustworthiness (rigour) of a stu...
Rape Trauma Syndrome
The authors interviewed and followed 146 patients admitted during a one-year period to the emergency ward of a city hospital with a presenting complaint of having been raped. Ba...
The Surviving Sepsis Campaign: Results of an international guideline-based performance improvement program targeting severe sepsis*
The Campaign was associated with sustained, continuous quality improvement in sepsis care. Although not necessarily cause and effect, a reduction in reported hospital mortality ...
Sleep-Disordered Breathing in Community-Dwelling Elderly
These are the final results of a survey of sleep-disordered breathing, which examined objective and subjective information from a large randomly selected elderly sample. We rand...
Control of Inflammation, Cytokine Expression, and Germinal Center Formation by BCL-6
The gene encoding the BCL-6 transcriptional repressor is frequently translocated and mutated in diffuse large cell lymphoma. Mice with a disrupted BCL-6 gene developed myocardit...
Early Lactate-Guided Therapy in Intensive Care Unit Patients
In patients with hyperlactatemia on ICU admission, lactate-guided therapy significantly reduced hospital mortality when adjusting for predefined risk factors. As this was consis...
Chronic Cough: The Spectrum and Frequency of Causes, Key Components of the Diagnostic Evaluation, and Outcome of Specific Therapy
A successful, systematic, anatomic, diagnostic protocol for evaluating patients with chronic cough was presented in 1981. To determine whether it was still valid, we prospective...