Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

Abstract

Vaccination of nonhuman primates with mRNA-1273 induced robust SARS-CoV-2 neutralizing activity, rapid protection in the upper and lower airways, and no pathologic changes in the lung. (Funded by the National Institutes of Health and others.).

Keywords

VirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BiologyCoronavirus disease 2019 (COVID-19)Messenger RNAMedicineGeneticsInfectious disease (medical specialty)Internal medicineGene

Affiliated Institutions

National Institutes of Health US

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Publication Info

Year: 2020
Type: article
Volume: 383
Issue: 16
Pages: 1544-1555
Citations: 1134
Access: Closed

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APA Style

                            
                                
                                    Kizzmekia S. Corbett, 
                                
                                    Barbara J. Flynn, 
                                
                                    Kathryn E. Foulds
                                
                                et al.
                            
                            (2020). 
                            Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates. 
                            New England Journal of Medicine
                            , 383
                            (16)
                            , 1544-1555.
                            https://doi.org/10.1056/nejmoa2024671
                        

Identifiers

DOI: 10.1056/nejmoa2024671