Oxidative stress, aging, and diseases
Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and exogenous processes, and their negative effects are neutralized by antioxidant defenses. Oxida...
Publications
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178 publications
Effect size, confidence interval and statistical significance: a practical guide for biologists
Abstract Null hypothesis significance testing (NHST) is the dominant statistical approach in biology, although it has many, frequently unappreciated, problems. Most importantly,...
Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU
Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design: Thirty-two intern...
CODA: convergence diagnosis and output analysis for MCMC
[1st paragraph] At first sight, Bayesian inference with Markov Chain Monte Carlo (MCMC) appears to be straightforward. The user defines a full probability model, perhaps using o...
Problem Behavior and Psychosocial Development: A Longitudinal Study of Youth
This study is the 2nd phase of a long-term program of research on problem behavior. The approach to theory testing involves a longitudinal design. The study plots trajectories...
Shape modeling with front propagation: a level set approach
Shape modeling is an important constituent of computer vision as well as computer graphics research. Shape models aid the tasks of object representation and recognition. This pa...
Takeover Bids, The Free-Rider Problem, and the Theory of the Corporation
It is commonly thought that a widely held corporation that is not being run in the interest of its shareholders will be vulnerable to a takeover bid. We show that this is false,...
Similarity Search in High Dimensions via Hashing
The nearest- or near-neighbor query problems arise in a large variety of database applications, usually in the context of similarity searching. Of late, there has been increasin...
A Historical Comparison of Resource-Based Theory and Five Schools of Thought Within Industrial Organization Economics: Do We Have a New Theory of the Firm?
A resource-based approach to strategic management focuses on costly-to-copy attributes of the firm as sources of economic rents and, therefore, as the fundamental drivers of per...
What Firms Do? Coordination, Identity, and Learning
Firms are organizations that represent social knowledge of coordination and learning. But why should their boundaries demarcate quantitative shifts in the knowledge and capabili...
Transfer of Large-Area Graphene Films for High-Performance Transparent Conductive Electrodes
Graphene, a two-dimensional monolayer of sp(2)-bonded carbon atoms, has been attracting great interest due to its unique transport properties. One of the promising applications ...
2003 European Society of Hypertension???European Society of Cardiology guidelines for the management of arterial hypertension*
Conflict of interest disclosures are given in the Appendix. Correspondence and requests for reprints to Professor Alberto Zanchetti, Centro di Fisiologia Clinica e Ipertensione,...