Embryonic Stem Cell Lines Derived from Human Blastocysts
Human blastocyst-derived, pluripotent cell lines are described that have normal karyotypes, express high levels of telomerase activity, and express cell surface markers that cha...
Publications
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1,290 publications
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
The cBioPortal enables integration, visualization, and analysis of multidimensional cancer genomic and clinical data.
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
Ipilimumab, with or without a gp100 peptide vaccine, as compared with gp100 alone, improved overall survival in patients with previously treated metastatic melanoma. Adverse eve...
Evaluating Goodness-of-Fit Indexes for Testing Measurement Invariance
Abstract Measurement invariance is usually tested using Multigroup Confirmatory Factor Analysis, which examines the change in the goodness-of-fit index (GFI) when cross-group co...
A Multi-Modal Distributed Real-Time IoT System for Urban Traffic Control (Invited Paper)
Traffic congestion is one of the growing urban problem with associated problems like fuel wastage, loss of lives, and slow productivity. The existing traffic system uses program...
TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data
The rapid development of high-throughput sequencing techniques has led biology into the big-data era. Data analyses using various bioinformatics tools rely on programming a...
Integrating single-cell transcriptomic data across different conditions, technologies, and species
Computational single-cell RNA-seq (scRNA-seq) methods have been successfully applied to experiments representing a single condition, technology, or species to discover and defin...
The Sequence of the Human Genome
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp ...
A Global Geometric Framework for Nonlinear Dimensionality Reduction
Scientists working with large volumes of high-dimensional data, such as global climate patterns, stellar spectra, or human gene distributions, regularly confront the problem of ...
Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
Antimicrobial resistance (AMR) poses a major threat to human health around the world. Previous publications have estimated the effect of AMR on incidence, deaths, hospital lengt...
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
The CONSORT statement is used worldwide to improve the reporting of randomised controlled trials. Kenneth Schulz and colleagues describe the latest version, CONSORT 2010, which ...