Publications
Explore 441 academic publications
Granules of the Human Neutrophilic Polymorphonuclear Leukocyte
POLYMORPHONUCLEAR leukocytes were discovered by Paul Ehrlich,[1][1] when fixation and staining techniques made it possible to identify the lobulated nucleus and the granules tha...
Polarizable Atomic Multipole Water Model for Molecular Mechanics Simulation
A new classical empirical potential is proposed for water. The model uses a polarizable atomic multipole description of electrostatic interactions. Multipoles through the quadru...
Development and Validation of the HScore, a Score for the Diagnosis of Reactive Hemophagocytic Syndrome
Objective Because it has no unique clinical, biologic, or histologic features, reactive hemophagocytic syndrome may be difficult to distinguish from other diseases such as sever...
Causal Inferences in Nonexperimental Research
Taking an exploratory rather than a dogmatic approach to the problem, this book pulls together materials bearing on casual inference that are widely scattered in the philosophic...
SARS: Systematic Review of Treatment Effects
Despite an extensive literature reporting on SARS treatments, it was not possible to determine whether treatments benefited patients during the SARS outbreak. Some may have been...
Probing the interaction between two single molecules: fluorescence resonance energy transfer between a single donor and a single acceptor.
We extend the sensitivity of fluorescence resonance energy transfer (FRET) to the single molecule level by measuring energy transfer between a single donor fluorophore and a sin...
The National Lung Screening Trial: Overview and Study Design
The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older c...
Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine
At 35 days, NVX-CoV2373 appeared to be safe, and it elicited immune responses that exceeded levels in Covid-19 convalescent serum. The Matrix-M1 adjuvant induced CD4+ T-cell res...
The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration
The quality of reporting of studies of diagnostic accuracy is less than optimal. Complete and accurate reporting is necessary to enable readers to assess the potential for bias ...