Publications
Explore 400 academic publications
Refining the Global Spatial Limits of Dengue Virus Transmission by Evidence-Based Consensus
The map produced here provides a list of 128 countries for which there is good evidence of dengue occurrence, including 36 countries that have previously been classified as deng...
Direct isolation of human central nervous system stem cells
Stem cells, which are clonogenic cells with self-renewal and multilineage differentiation properties, have the potential to replace or repair damaged tissue. We have directly is...
The substantia nigra of the human brain
To achieve accuracy in studying the patterns of loss of midbrain dopamine-containing neurons in Parkinson's disease, we used compartmental patterns of calbindin D(28K) immunosta...
The landscape of cancer genes and mutational processes in breast cancer
All cancers carry somatic mutations in their genomes. A subset, known as driver mutations, confer clonal selective advantage on cancer cells and are causally implicated in oncog...
AGE STANDARDIZATION OF RATES: A NEW WHO STANDARD
A recent WHO analysis has revealed the need for a new world standard population (see attached table). This has become particularly pertinent given the rapid and continued declin...
Primary Bioassay of Human Tumor Stem Cells
A simple method has been developed to support human tumor stem cell colony growth in soft agar. The technique appears suitable for culture of a variety of neoplasms of differing...
Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2
Background— Angiotensin-converting enzyme 2 (ACE2) has emerged as a novel regulator of cardiac function and arterial pressure by converting angiotensin II (Ang II) into the vaso...
HGVS Recommendations for the Description of Sequence Variants: 2016 Update
The consistent and unambiguous description of sequence variants is essential to report and exchange information on the analysis of a genome. In particular, DNA diagnostics criti...
Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents
This Clinical Report was retired October 2012. Rickets in infants attributable to inadequate vitamin D intake and decreased exposure to sunlight continues to be reported in the ...