Abstract
A simple method has been developed to support human tumor stem cell colony growth in soft agar. The technique appears suitable for culture of a variety of neoplasms of differing histopathology. Tumor stem cell colonies arising from different types of cancer have differing growth characteristics and colony morphology. This bioassay should be suitable for clinical studies of effects of anticancer drugs or irradiation on human tumor stem cells.
Keywords
BioassayStem cellBiologyTumor cellsCancer researchCell biologyGenetics
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Publication Info
- Year
- 1977
- Type
- article
- Volume
- 197
- Issue
- 4302
- Pages
- 461-463
- Citations
- 1639
- Access
- Closed
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Cite This
Anne W. Hamburger,
Sydney E. Salmon
(1977).
Primary Bioassay of Human Tumor Stem Cells.
Science
, 197
(4302)
, 461-463.
https://doi.org/10.1126/science.560061
Identifiers
- DOI
- 10.1126/science.560061