Real-Time DNA Sequencing from Single Polymerase Molecules
We present single-molecule, real-time sequencing data obtained from a DNA polymerase performing uninterrupted template-directed synthesis using four distinguishable fluorescentl...
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1,520 publications
A measure of population subdivision based on microsatellite allele frequencies.
Abstract A new measure of the extent of population subdivision as inferred from allele frequencies at microsatellite loci is proposed and tested with computer simulations. This ...
Word association norms, mutual information, and lexicography
The term word association is used in a very particular sense in the psycholinguistic literature. (Generally speaking, subjects respond quicker than normal to the word nurse if i...
The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews
This project has produced an evidence based quality assessment tool to be used in systematic reviews of diagnostic accuracy studies. Further work to determine the usability and ...
Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study
Abstract Objective To characterise the clinical features of patients admitted to hospital with coronavirus disease 2019 (covid-19) in the United Kingdom during the growth phase ...
Assessment of Clinical Criteria for Sepsis
Among ICU encounters with suspected infection, the predictive validity for in-hospital mortality of SOFA was not significantly different than the more complex LODS but was stati...
Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
BACKGROUND Nivolumab plus ipilimumab or nivolumab alone resulted in longer progression-free and overall survival than ipilimumab alone in a trial involving patients with advance...
A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma
Many human melanoma tumors express antigens that are recognized in vitro by cytolytic T lymphocytes (CTLs) derived from the tumor-bearing patient. A gene was identified that dir...