Montgomery Slatkin

Finding the missing heritability of complex diseases

A measure of population subdivision based on microsatellite allele frequencies.

Abstract A new measure of the extent of population subdivision as inferred from allele frequencies at microsatellite loci is proposed and tested with computer simulations. This ...

Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm

We generalize an approach suggested by Hill (Heredity, 33, 229-239, 1974) for testing for significant association among alleles at two loci when only genotype and not haplotype ...

A Quasi-equilibrium theory of the distribution of rare alleles in a subdivided population

Incorporating Genotypes of Relatives into a Test of Linkage Disequilibrium

Estimation of levels of gene flow from DNA sequence data.

Abstract We compare the utility of two methods for estimating the average levels of gene flow from DNA sequence data. One method is based on estimating FST from frequencies at p...

A correction to the exact test based on the Ewens sampling distribution

Summary The exact test for neutrality based on the Ewens sampling distribution described previously (Slatkin, 1994) is not correct. The problem is that the test as described is ...