Assessment of Clinical Criteria for Sepsis

Abstract

Among ICU encounters with suspected infection, the predictive validity for in-hospital mortality of SOFA was not significantly different than the more complex LODS but was statistically greater than SIRS and qSOFA, supporting its use in clinical criteria for sepsis. Among encounters with suspected infection outside of the ICU, the predictive validity for in-hospital mortality of qSOFA was statistically greater than SOFA and SIRS, supporting its use as a prompt to consider possible sepsis.

Keywords

Affiliated Institutions

• Guy's and St Thomas' NHS Foundation Trust GB
• University of Pittsburgh US
• Health Sciences Centre CA
• Feinstein Institute for Medical Research US
• Kaiser Permanente US
• University College London GB
• University of Michigan US
• University of Toronto CA
• Jena University Hospital DE
• Bury College GB
• Sunnybrook Health Science Centre CA
• Schneider Children's Hospital US
• University of Washington US
• VA Center for Clinical Management Research US

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