Publications
Explore 887 academic publications
Pfam: The protein families database in 2021
Abstract The Pfam database is a widely used resource for classifying protein sequences into families and domains. Since Pfam was last described in this journal, over 350 new fam...
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
Abstract Motivation: Homology models of proteins are of great interest for planning and analysing biological experiments when no experimental three-dimensional structures are av...
Stable signal recovery from incomplete and inaccurate measurements
Abstract Suppose we wish to recover a vector x 0 ∈ ℝ 𝓂 (e.g., a digital signal or image) from incomplete and contaminated observations y = A x 0 + e ; A is an 𝓃 × 𝓂 matrix wi...
Comparison of multiple Amber force fields and development of improved protein backbone parameters
Abstract The ff94 force field that is commonly associated with the Amber simulation package is one of the most widely used parameter sets for biomolecular simulation. After a de...
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
Funnel plots, and tests for funnel plot asymmetry, have been widely used to examine bias in the results of meta-analyses. Funnel plot asymmetry should not be equated with public...
Additive logistic regression: a statistical view of boosting (With discussion and a rejoinder by the authors)
Boosting is one of the most important recent developments in\nclassification methodology. Boosting works by sequentially applying a\nclassification algorithm to reweighted versi...
Planetary Boundaries: Exploring the Safe Operating Space for Humanity
"Anthropogenic pressures on the Earth System have reached a scale where abrupt global environmental change can no longer be excluded. We propose a new approach to global sustain...