Publications

A method and server for predicting damaging missense mutations

Robust enumeration of cell subsets from tissue expression profiles

We introduce CIBERSORT, a method for characterizing cell composition of complex tissues from their gene expression profiles. When applied to enumeration of hematopoietic subsets...

Twelve years of SAMtools and BCFtools

Abstract Background SAMtools and BCFtools are widely used programs for processing and analysing high-throughput sequencing data. They include tools for file format conversion an...

RNA-Seq: a revolutionary tool for transcriptomics

BEAST: Bayesian evolutionary analysis by sampling trees

BEAST is a powerful and flexible evolutionary analysis package for molecular sequence variation. It also provides a resource for the further development of new models and statis...

A new coronavirus associated with human respiratory disease in China

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

lin-4 is essential for the normal temporal control of diverse postembryonic developmental events in C. elegans. lin-4 acts by negatively regulating the level of LIN-14 protein, ...

Predicting transmembrane protein topology with a hidden markov model: application to complete genomes11Edited by F. Cohen

SWISS-MODEL: homology modelling of protein structures and complexes

Homology modelling has matured into an important technique in structural biology, significantly contributing to narrowing the gap between known protein sequences and experimenta...

<i>Planck</i> 2018 results

We present cosmological parameter results from the final full-mission Planck measurements of the cosmic microwave background (CMB) anisotropies, combining information from the t...

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells