Hallmarks of Cancer: New Dimensions
Abstract The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underlying...
Publications
Explore 905 academic publications
Showing 12 of
905 publications
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.
We constructed a series of recombinant genomes which directed expression of the enzyme chloramphenicol acetyltransferase (CAT) in mammalian cells. The prototype recombinant in t...
The MR-Base platform supports systematic causal inference across the human phenome
Results from genome-wide association studies (GWAS) can be used to infer causal relationships between phenotypes, using a strategy known as 2-sample Mendelian randomization (2SM...
The spread of true and false news online
Lies spread faster than the truth There is worldwide concern over false news and the possibility that it can influence political, economic, and social well-being. To understand ...
The Complete Genome Sequence of <i>Escherichia coli</i> K-12
The 4,639,221–base pair sequence of Escherichia coli K-12 is presented. Of 4288 protein-coding genes annotated, 38 percent have no attributed function. Comparison with five othe...
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
Abstract Motivation: Homology models of proteins are of great interest for planning and analysing biological experiments when no experimental three-dimensional structures are av...
Stable signal recovery from incomplete and inaccurate measurements
Abstract Suppose we wish to recover a vector x 0 ∈ ℝ 𝓂 (e.g., a digital signal or image) from incomplete and contaminated observations y = A x 0 + e ; A is an 𝓃 × 𝓂 matrix wi...
A Rapid Bootstrap Algorithm for the RAxML Web Servers
Despite recent advances achieved by application of high-performance computing methods and novel algorithmic techniques to maximum likelihood (ML)-based inference programs, the m...
Homo Sacer
One of Italy's most original philosophers aims to connect the problem of pure possibility, potentiality, and power with the problem of political and social ethics in a context w...
OrthoFinder: phylogenetic orthology inference for comparative genomics
Abstract Here, we present a major advance of the OrthoFinder method. This extends OrthoFinder’s high accuracy orthogroup inference to provide phylogenetic inference of orthologs...
Honeycomb Carbon: A Review of Graphene
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTHoneycomb Carbon: A Review of GrapheneMatthew J. Allen†, Vincent C. Tung‡, and Richard B. Kaner*†‡View Author Information Department o...