Abstract

We estimated that cART halved the average mortality rate in HIV-infected individuals. The mortality reduction was greater in those with worse prognosis at the start of follow-up.

Keywords

CartMarginal structural modelHazard ratioConfoundingMedicineConfidence intervalAntiretroviral therapyInternal medicineProportional hazards modelProspective cohort studyCohort studyCohortHuman immunodeficiency virus (HIV)Viral loadImmunologyDemography

MeSH Terms

AdultAntiretroviral TherapyHighly ActiveCD4 Lymphocyte CountDrug Administration ScheduleDrug TherapyCombinationEuropeFemaleHIV InfectionsHIV-1HumansMaleMiddle AgedProportional Hazards ModelsTime FactorsUnited StatesViral Load

Related Publications

Publication Info

Year
2009
Type
article
Volume
24
Issue
1
Pages
123-137
Citations
460
Access
Closed

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

460
OpenAlex
8
Influential
357
CrossRef

Cite This

The HIV-CAUSAL Collaboration (2009). The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals. AIDS , 24 (1) , 123-137. https://doi.org/10.1097/qad.0b013e3283324283

Identifiers

DOI
10.1097/qad.0b013e3283324283
PMID
19770621
PMCID
PMC2920287

Data Quality

Data completeness: 86%