Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More

Keywords

BiologyEffectorLineage (genetic)CD8ImmunologyCell lineageReceptorCell biologyCellular differentiationImmune systemGeneticsGene

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Publication Info

Year
1988
Type
review
Volume
6
Issue
1
Pages
309-326
Citations
301
Access
Closed

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Cite This

H von Boehmer (1988). The Developmental Biology of T Lymphocytes. Annual Review of Immunology , 6 (1) , 309-326. https://doi.org/10.1146/annurev.iy.06.040188.001521

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DOI
10.1146/annurev.iy.06.040188.001521