The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

Bruce Beutler; Anthony Cerami

doi:10.1146/annurev.iy.07.040189.003205

Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More

Keywords

BiologyEffectorMediatorTumor necrosis factor alphaImmunologyCell biologyCD8Lineage (genetic)ReceptorImmune systemGeneticsGene

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Publication Info

Year: 1989
Type: review
Volume: 7
Issue: 1
Pages: 625-655
Citations: 1682
Access: Closed

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APA Style

                            
                                    Bruce Beutler, 
                                
                                    Anthony Cerami
                                
                            (1989). 
                            The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response. 
                            Annual Review of Immunology
                            , 7
                            (1)
                            , 625-655.
                            https://doi.org/10.1146/annurev.iy.07.040189.003205

Identifiers

DOI: 10.1146/annurev.iy.07.040189.003205