Abstract
Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More
Keywords
BiologyEffectorLymphokineCD8SecretionLineage (genetic)ImmunologyCell biologyReceptorImmune systemGeneticsEndocrinologyGene
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Publication Info
- Year
- 1989
- Type
- review
- Volume
- 7
- Issue
- 1
- Pages
- 145-173
- Citations
- 7559
- Access
- Closed
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Cite This
Tim R. Mosmann,
Robert L. Coffman
(1989).
TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties.
Annual Review of Immunology
, 7
(1)
, 145-173.
https://doi.org/10.1146/annurev.iy.07.040189.001045
Identifiers
- DOI
- 10.1146/annurev.iy.07.040189.001045