Abstract

First-order nonlinear differential-delay equations describing physiological control systems are studied. The equations display a broad diversity of dynamical behavior including limit cycle oscillations, with a variety of wave forms, and apparently aperiodic or "chaotic" solutions. These results are discussed in relation to dynamical respiratory and hematopoietic diseases.

Keywords

Aperiodic graphLimit cycleDynamical systems theoryOscillation (cell signaling)Nonlinear systemChaoticLimit (mathematics)Statistical physicsControl theory (sociology)PhysicsVariety (cybernetics)Synchronization of chaosCHAOS (operating system)MathematicsControl of chaosControl (management)Mathematical analysisComputer scienceBiologyQuantum mechanics

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Publication Info

Year
1977
Type
article
Volume
197
Issue
4300
Pages
287-289
Citations
4007
Access
Closed

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Cite This

Michael C. Mackey, Leon Glass (1977). Oscillation and Chaos in Physiological Control Systems. Science , 197 (4300) , 287-289. https://doi.org/10.1126/science.267326

Identifiers

DOI
10.1126/science.267326