Abstract

The administration of NXY-059 within six hours after the onset of acute ischemic stroke significantly improved the primary outcome (reduced disability at 90 days), but it did not significantly improve other outcome measures, including neurologic functioning as measured by the NIHSS score. Additional research is needed to confirm whether NXY-059 is beneficial in ischemic stroke. (ClinicalTrials.gov number, NCT00119626.).

Keywords

MedicineModified Rankin ScaleConfidence intervalStroke (engine)PlaceboOdds ratioPost-hoc analysisAnesthesiaRandomized controlled trialInternal medicineCardiologyPhysical therapyIschemic strokeIschemia

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Publication Info

Year
2006
Type
article
Volume
354
Issue
6
Pages
588-600
Citations
654
Access
Closed

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Kennedy R. Lees, Justin A. Zivin, Tim Ashwood et al. (2006). NXY-059 for Acute Ischemic Stroke. New England Journal of Medicine , 354 (6) , 588-600. https://doi.org/10.1056/nejmoa052980

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DOI
10.1056/nejmoa052980