Abstract
Abstract Meta‐analyses involving the synthesis of evidence from cluster randomization trials are being increasingly reported. These analyses raise challenging methodologic issues beyond those raised by meta‐analyses which include only individually randomized trials. In this paper we review and comment on a selected number of these issues, including problems of study heterogeneity, difficulties in estimating design effects from individual trials and the choice of statistical methods. Copyright © 2002 John Wiley & Sons, Ltd.
Keywords
Meta-analysisRandomizationRandomized controlled trialCluster (spacecraft)Computer scienceResearch designEconometricsStatisticsMedicineMathematicsSurgery
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Publication Info
- Year
- 2002
- Type
- article
- Volume
- 21
- Issue
- 19
- Pages
- 2971-2980
- Citations
- 729
- Access
- Closed
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Cite This
Allan Donner,
Neil Klar
(2002).
Issues in the meta‐analysis of cluster randomized trials.
Statistics in Medicine
, 21
(19)
, 2971-2980.
https://doi.org/10.1002/sim.1301
Identifiers
- DOI
- 10.1002/sim.1301