Keywords
Affiliated Institutions
Related Publications
Human Nod1 Confers Responsiveness to Bacterial Lipopolysaccharides
The immune response to microbial pathogens is initiated by recognition of specific pathogen components by host cells both at the cell surface and in the cytosol. While the respo...
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
SUMMARY The innate immune system constitutes the first line of defense against invading microbial pathogens and relies on a large family of pattern recognition receptors (PRRs),...
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
Macrophages orchestrate innate immunity by phagocytosing pathogens and coordinating inflammatory responses. Effective defence requires the host to discriminate between different...
Phylogenetic Perspectives in Innate Immunity
The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent data have highlig...
Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
Recognition by innate immune cells of the pathogen associated molecular patterns (PAMP) lipopolysaccharide (LPS) from Gram-negative bacteria and bacterial CpG-DNA depends on Tol...
Publication Info
- Year
- 2002
- Type
- review
- Volume
- 10
- Issue
- 4
- Pages
- 193-199
- Citations
- 190
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1016/s0966-842x(02)02334-x