Abstract
The 97-megabase genomic sequence of the nematode Caenorhabditis elegans reveals over 19,000 genes. More than 40 percent of the predicted protein products find significant matches in other organisms. There is a variety of repeated sequences, both local and dispersed. The distinctive distribution of some repeats and highly conserved genes provides evidence for a regional organization of the chromosomes.
Keywords
Related Publications
Genetic pathways that regulate ageing in model organisms
Searches for genes involved in the ageing process have been made in genetically tractable model organisms such as yeast, the nematode Caenorhabditis elegans, Drosophila melanoga...
Integrative Analysis of the <i>Caenorhabditis elegans</i> Genome by the modENCODE Project
From Genome to Regulatory Networks For biologists, having a genome in hand is only the beginning—much more investigation is still needed to characterize how the genome is used t...
The Genome Sequence of <i>Drosophila melanogaster</i>
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular...
High-Throughput Gene Mapping in <i>Caenorhabditis elegans</i>
Positional cloning of mutations in model genetic systems is a powerful method for the identification of targets of medical and agricultural importance. To facilitate the high-th...
Structural diversity and functional implications of the eukaryotic TDP gene family
TDP-43 is an RNA-binding protein that functions in mammalian cells in transcriptional repression and exon skipping. The gene encoding TDP-43 (HGMW-approved gene symbol TARDBP) i...
Publication Info
- Year
- 1998
- Type
- review
- Volume
- 282
- Issue
- 5396
- Pages
- 2012-2018
- Citations
- 3834
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1126/science.282.5396.2012