Genetic pathways that regulate ageing in model organisms
Searches for genes involved in the ageing process have been made in genetically tractable model organisms such as yeast, the nematode Caenorhabditis elegans, Drosophila melanoga...
Publications
3 shown<i>daf-16</i> : An HNF-3/forkhead Family Member That Can Function to Double the Life-Span of <i>Caenorhabditis elegans</i>
The wild-type Caenorhabditis elegans nematode ages rapidly, undergoing development, senescence, and death in less than 3 weeks. In contrast, mutants with reduced activity of the...
A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
In many organisms, dietary restriction appears to extend lifespan, at least in part, by down-regulating the nutrient-sensor TOR (Target Of Rapamycin). TOR inhibition elicits aut...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 3,571
- Institution
- University of California, San Francisco
External Links
Identifiers
- ORCID
- 0000-0003-3446-2636
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.