Abstract

Systematic analysis of the Arabidopsis genome provides a basis for detailed studies of genome structure and evolution. Members of multigene families were mapped, and random sequence alignment was used to identify regions of extended similarity in the Arabidopsis genome. Detailed analysis showed that the number, order, and orientation of genes were conserved over large regions of the genome, revealing extensive duplication covering the majority of the known genomic sequence. Fine mapping analysis showed much rearrangement, resulting in a patchwork of duplicated regions that indicated deletion, insertion, tandem duplication, inversion, and reciprocal translocation. The implications of these observations for evolution of the Arabidopsis genome as well as their usefulness for analysis and annotation of the genomic sequence and in comparative genomics are discussed.

Keywords

ArabidopsisGene duplicationGenomeBiologyComparative genomicsSegmental duplicationGeneticsComputational biologyGenome evolutionGenomicsGeneGenome projectTandem exon duplicationWhole genome sequencingGene family

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Year
2000
Type
article
Volume
12
Issue
7
Pages
1093-1101
Citations
513
Access
Closed

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Guillaume Blanc, Abdelali Bara­kat, Romain Guyot et al. (2000). Extensive Duplication and Reshuffling in the Arabidopsis Genome. The Plant Cell , 12 (7) , 1093-1101. https://doi.org/10.1105/tpc.12.7.1093

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DOI
10.1105/tpc.12.7.1093