Abstract

We present version 6 of the DNA Sequence Polymorphism (DnaSP) software, a new version of the popular tool for performing exhaustive population genetic analyses on multiple sequence alignments. This major upgrade incorporates novel functionalities to analyze large data sets, such as those generated by high-throughput sequencing technologies. Among other features, DnaSP 6 implements: 1) modules for reading and analyzing data from genomic partitioning methods, such as RADseq or hybrid enrichment approaches, 2) faster methods scalable for high-throughput sequencing data, and 3) summary statistics for the analysis of multi-locus population genetics data. Furthermore, DnaSP 6 includes novel modules to perform single- and multi-locus coalescent simulations under a wide range of demographic scenarios. The DnaSP 6 program, with extensive documentation, is freely available at http://www.ub.edu/dnasp.

Keywords

BiologyCoalescent theoryComputational biologyDNA sequencingLocus (genetics)ScalabilitySoftwarePopulationGeneticsDocumentationData miningComputer scienceDNADatabaseGeneProgramming languagePhylogenetics

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Year
2017
Type
article
Volume
34
Issue
12
Pages
3299-3302
Citations
6957
Access
Closed

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Julio Rozas, Albert Ferrer-Mata, Juan Carlos Sánchez-DelBarrio et al. (2017). DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets. Molecular Biology and Evolution , 34 (12) , 3299-3302. https://doi.org/10.1093/molbev/msx248

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DOI
10.1093/molbev/msx248