Abstract
The results demonstrate the essential role of multiple loci in recovering population size dynamics. Multi-locus data from a small number of individuals can precisely recover past bottlenecks in population size which can not be characterized by analysis of a single locus. We also demonstrate that sequence data quality is important because even moderate levels of sequencing errors result in a considerable decrease in estimation accuracy for realistic levels of population genetic variability.
Keywords
Coalescent theoryPopulationBiologyEffective population sizePopulation sizeBayesian probabilityLocus (genetics)InferenceMarkov chain Monte CarloBayes' theoremStatisticsEvolutionary biologyGeneticsComputer scienceMathematicsArtificial intelligenceGenetic variationPhylogeneticsGene
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Publication Info
- Year
- 2008
- Type
- article
- Volume
- 8
- Issue
- 1
- Pages
- 289-289
- Citations
- 769
- Access
- Closed
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Cite This
Joseph Heled,
Alexei J. Drummond
(2008).
Bayesian inference of population size history from multiple loci.
BMC Evolutionary Biology
, 8
(1)
, 289-289.
https://doi.org/10.1186/1471-2148-8-289
Identifiers
- DOI
- 10.1186/1471-2148-8-289