A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia

Hartmut Döhner; Bob Löwenberg; Peter J.M. Valk; Eric M. Bindels; Wouter de Laat; Ruud Delwel; Stefan Gröschel; Mathijs A. Sanders; Remco M. Hoogenboezem; Elzo de Wit; Britta A. M. Bouwman; Claudia Erpelinck-Verschueren; Vincent H. J. van der Velden; Marije Havermans; Roberto Avellino; Kirsten van Lom; Elwin Rombouts; Mark van Duin; Konstanze Döhner; H. Berna Beverloo; James E. Bradner

doi:10.1016/j.cell.2014.02.019

Keywords

BiologyEnhancerHaploinsufficiencyGene silencingEctopic expressionGeneticsGATA2Cancer researchGeneFunctional genomicsRegulation of gene expressionCell biologyPhenotypeGene expressionGenomeGenomics

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Publication Info

Year: 2014
Type: article
Volume: 157
Issue: 2
Pages: 369-381
Citations: 685
Access: Closed

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APA Style

                            
                                
                                    Hartmut Döhner, 
                                
                                    Bob Löwenberg, 
                                
                                    Peter J.M. Valk
                                
                                et al.
                            
                            (2014). 
                            A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia. 
                            Cell
                            , 157
                            (2)
                            , 369-381.
                            https://doi.org/10.1016/j.cell.2014.02.019
                        

Identifiers

DOI: 10.1016/j.cell.2014.02.019