Pennsylvania State University

Basic local alignment search tool

The Sequence of the Human Genome

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp ...

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

Abstract: We present the derivation of a new molecular mechanical force field for simulating the structures, conformational energies, and interaction energies of proteins, nucle...

Ecological responses to recent climate change

The Amber biomolecular simulation programs

Abstract We describe the development, current features, and some directions for future development of the Amber package of computer programs. This package evolved from a program...

The Astropy Project: Building an Open-science Project and Status of the v2.0 Core Package^*

Abstract The Astropy Project supports and fosters the development of open-source and openly developed Python packages that provide commonly needed functionality to the astronomi...

Qualitative data analysis (2nd ed)

Numerical Study of Convection Observed during the Winter Monsoon Experiment Using a Mesoscale Two-Dimensional Model

Abstract A two-dimensional version of the Pennsylvania State University mesoscale model has been applied to Winter Monsoon Experiment data in order to simulate the diurnally occ...

Progress, Challenges, and Opportunities in Two-Dimensional Materials Beyond Graphene

Graphene's success has shown that it is possible to create stable, single and few-atom-thick layers of van der Waals materials, and also that these materials can exhibit fascina...

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

Galaxy (homepage: https://galaxyproject.org, main public server: https://usegalaxy.org) is a web-based scientific analysis platform used by tens of thousands of scientists acros...