Merck Canada Inc. (Canada) - Academic Profile

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Caspases: killer proteases

Donald W. Nicholson , Nancy A. Thornberry

1997 Trends in Biochemical Sciences 2417 citations

Human ICE/CED-3 Protease Nomenclature

Emad S. Alnemri , David J. Livingston , Donald W. Nicholson +4 more

1996 Cell 2379 citations

A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

Nancy A. Thornberry , Thomas A. Rano , Erin P. Peterson +9 more

There is compelling evidence that members of the caspase (interleukin-1beta converting enzyme/CED-3) family of cysteine proteases and the cytotoxic lymphocyte-derived serine pro...

1997 Journal of Biological Chemistry 2066 citations

Trifluoroethylamines as amide isosteres in inhibitors of cathepsin K

W. Cameron Black , Christopher I. Bayly , Dana Davis +11 more

2005 Bioorganic & Medicinal Chemistry Letters 135 citations

Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding

Nathalie Chauret , Daniel Guay , Chun Li +6 more

2002 Bioorganic & Medicinal Chemistry Letters 57 citations

Affiliated Researchers

Institution Info

Type: company
Country: CA
Publications: 5
Citations: 7,054

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ROR: https://ror.org/00rz3ed53

Publications

Affiliated Researchers

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