Laboratoire de Chimie Organique

Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA.

A general and efficient transfection procedure, based on compacted lipopolyamine-coated plasmids, has been developed. The active species is obtained by simple addition of excess...

A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution

One of the facets of the host defense of higher insects is the rapid and transient synthesis, following bacterial challenge or trauma, of a battery of potent antibacterial pepti...

Synthetic and Structural Studies on [Fe₂(SR)₂(CN)<i>_x</i>(CO)₆_-<i>_x</i>]<i>^x</i>^- as Active Site Models for Fe-Only Hydrogenases

A series of models for the active site (H-cluster) of the iron-only hydrogenase enzymes (Fe-only H2-ases) were prepared. Treatment of MeCN solutions of Fe2(SR)2(CO)6 with 2 equi...

Sorbic acid iron tricarbonyl complex as resolving agent. Chiralsyntheses of 4-hydroxy nonenal and cariolic acid.

Application of molecular sieves in view of cleaner technology. Gas and liquid phase separations