Rüdiger von Kummer

Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke

Among patients with anterior circulation stroke who could be treated within 8 hours after symptom onset, stent retriever thrombectomy reduced the severity of post-stroke disabil...

Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke

The trial showed similar safety outcomes and no significant difference in functional independence with endovascular therapy after intravenous t-PA, as compared with intravenous ...

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

As compared with placebo, intravenous alteplase administered between 3 and 4.5 hours after the onset of symptoms significantly improved clinical outcomes in patients with acute ...

Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)

Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials

Guidelines for Management of Ischaemic Stroke and Transient Ischaemic Attack 2008

This article represents the update of the European Stroke Initiative Recommendations for Stroke Management. These guidelines cover both ischaemic stroke and transient ischaemic ...

Recanalization and Clinical Outcome of Occlusion Sites at Baseline CT Angiography in the Interventional Management of Stroke III Trial

Significant differences were identified between treatment arms for 24-hour recanalization in proximal occlusions; carotid T- or L-type and tandem ICA and M1 occlusions showed gr...

Endovascular Therapy Is Effective and Safe for Patients With Severe Ischemic Stroke

Background and Purpose— We assessed the effect of endovascular treatment in acute ischemic stroke patients with severe neurological deficit (National Institutes of Health Stroke...

Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke

Hemorrhagic Transformation Within 36 Hours of a Cerebral Infarct

Background and Purpose —The clinical correlates of the varying degrees of early hemorrhagic transformation of a cerebral infarct are unclear. We investigated the cohort of a ran...

Early Prediction of Irreversible Brain Damage after Ischemic Stroke at CT

After ischemic stroke, x-ray hypoattenuation at CT is highly specific for irreversible ischemic brain damage if detection occurs within the first 6 hours. Patients without hypoa...