Publications
5 shownSelf-eating and self-killing: crosstalk between autophagy and apoptosis
Apoptotic cell death is mediated by molecular pathways that culminate in the activation of a family of cysteine proteases, known as the caspases, which orchestrate the dismantli...
Functional and physical interaction between Bcl‐XL and a BH3‐like domain in Beclin‐1
The anti-apoptotic proteins Bcl-2 and Bcl-X(L) bind and inhibit Beclin-1, an essential mediator of autophagy. Here, we demonstrate that this interaction involves a BH3 domain wi...
Regulation of autophagy by the inositol trisphosphate receptor
The reduction of intracellular 1,4,5-inositol trisphosphate (IP(3)) levels stimulates autophagy, whereas the enhancement of IP(3) levels inhibits autophagy induced by nutrient d...
Frequent Co-Authors
Researcher Info
- h-index
- 5
- Publications
- 5
- Citations
- 8,661
- Institution
- Institut Gustave Roussy
External Links
Identifiers
- ORCID
- 0000-0001-9760-7674
Impact Metrics
h-index
5
h-index: Number of publications with at least h citations each.